… of macroautophagy disruption, the degeneration is not widespread. Instead, preferential
vulnerability of neurons to macroautophagy … pyramidal neurons — points to neuronal subtype-…

… Selective autophagy uses the same core components of the nonselective macroautophagy
… did lead to neuronal and axonal dystrophy, degeneration of axon terminals, and eventual …

… Suggested links with psychiatric diseases Recent studies have provided some support for
the hypothesis that altered neuronal macroautophagy may contribute to depression, bipolar …

… Within neurons, it helps to remove damaged organelles … neuronal physiology. Here we
review the literature on the role of autophagy in maintaining neuronal stem cells and in neuronal …

… lysosome including nonspecific macroautophagy, substrate-… , in motor neurons early in
development in mice expressing a … unit function and motor neuron-dependent phenotypes could …

… how abnormalities of neuronal autophagy could serve as a pro-degenerative triggering … is
autophagy, in particular macroautophagy. Neuronal macroautophagy prevents cell toxicity by …

… Neuronal macroautophagy is an important mechanism that removes faulty intracellular
materials, being extremely efficient in neurons, … to halt neuronal dysfunction and degeneration. …

… Thus, neurons rely heavily on autophagy that constitutes a … located in the soma of neurons,
the robust, constitutive … of the roles of autophagy in neuronal health and disease. We …

… (neuro)developmental phenotypes and the predilection for certain (neuronal) tissues in the
… , 2) a combination of developmental and degenerative abnormalities evolving over time and 3…

… Macroautophagy (hereafter referred to as autophagy) plays a critical role in neuronal function
related to development and degeneration. … during striatal postnatal development, reaching …